Okogen’s focus is exclusively on diseases affecting the eye
We are initially targeting infectious conjunctivitis and have secondary programs in CMV retinitis and exotic viral infections.
Acute conjunctivitis, commonly known as ‘pink eye’, is one of the most frequent ocular diseases observed in emergency departments, urgent care facilities, ophthalmic clinics and pediatric departments. Viral conjunctivitis is the most frequent form of acute conjunctivitis, comprising up to 80% of cases of infectious origins, of which, adenoviruses cause up to 90% of cases. Currently, there are no approved therapeutics to treat adenoviral conjunctivitis.
Cytomegalovirus (CMV) Retinitis is a very serious viral eye infection affecting the retina. CMV, a member of the herpesvirus family, most often causes disease in those patients with compromised immune systems. Today’s antiviral regimens are expensive and some patients have disease that does not respond to first-line therapy.
Greater than 6 million Americans annually get acute conjunctivitis. Outside the USA, this number is approximately 30 million. Of the cases in the USA, 70% of patients seek treatment, of which, it is believed that 80% is caused by viruses.